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  • Avatar priplelib says:

    Telaprevir Decrease AUC by 92 Systemic Hormonal Contraceptives Prevention or Management Advise patients to change to non hormonal methods of birth control during rifampin therapy Estrogens Decrease exposure Progestins Anticonvulsants Phenytoin d Decrease exposure d Antiarrhythmics Disopyramide Decrease exposure Mexiletine Decrease exposure Quinidine Decrease exposure Propafenone Decrease AUC by 50 67 Tocainide Decrease exposure Antiestrogens Tamoxifen Decrease AUC by 86 Tamoxifen Decrease steady state concentrations of toremifene in serum Antithrombotic Agents Clopidogrel Prevention or Management Concomitant use of clopidogrel and rifampin should be discouraged Increase active metabolite exposure and risk of bleeding Ticagrelor Prevention or Management Avoid use Decrease exposure Antipsychotics Haloperidol Decrease plasma concentrations by 70 Oral Anticoagulants Prevention or Management Perform prothrombin time daily or as frequently as necessary to establish and maintain the required dose of anticoagulant Warfarin Decrease exposure Antifungals Fluconazole Decrease AUC by 23 Itraconazole Prevention or Management Not recommended 2 weeks before and during itraconazole treatment Decrease exposure Ketoconazole Decrease exposure Beta blockers Metoprolol Decrease exposure Propranolol Decrease exposure Benzodiazepines Diazepam a, e Decrease exposure Benzodiazepine related drugs Zopiclone Decrease AUC by 82 Zolpidem Decrease AUC by 73 Calcium Channel Blockers e Diltiazem Decrease exposure Nifedipine f Decrease exposure Verapamil Decrease exposure Corticosteroids g Prednisolone Decrease exposure Cardiac Glycosides Digoxin Prevention or Management Measure serum digoxin concentrations before initiating rifampin buy cialis professional

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